It is extremely important for investigators to contact the CTRC Administration when preparing grant budgets and submissions. The CTRC charges for services and these costs must be included in all budgets. The CTRC Administrative Director can provide this information. In addition, it is strongly recommended that investigators include a letter of support from the appropriate CTRC Program Director when their grant submission proposes the use of the CTRC. For a letter from the pediatric CTRC Program Director, contact Carole Marcus, MBBCh, at marcus [at] email.chop.edu or by calling (267)426-5842. For a letter of support for a study utilizing the adult CTRC, contact the Program Director, Anne Cappola, MD, ScM, at acappola [at] uphs.upenn.edu. CTRC Administrative Directors are John Krall (pediatric) at krallj [at] email.chop.edu (267) 425- 1790 and Lorri Schieri (adult) at schieril [at] upenn.edu (215)573-0900.