Clinical and Translational
Research Center

Services & Facilities

Services and Facilities

The CTRC is comprised of various units and core services designed to facilitate the research process. Each unit or core is overseen by a director who has extensive expertise and serves as a resource for investigators and trainees. Investigators are strongly encouraged to discuss their proposed project with appropriate unit directors prior to submitting a proposal to the CTRC. Hours of operation for most core areas are Monday to Friday normal business hours; you must contact the core director prior to submission if your study requires off-hour services.  To submit a proposal, investigators complete an online application via the eResearch system. IRB submissions can be completed via the same mechanism simultaneous with the CTRC submission. The CTRC reviews each protocol submission; each protocol must have both IRB and CTRC approval prior to utilization of CTRC services and resources. Investigators who are not based at CHOP must contact CTRC Administrators for specific submission instructions.

Clik on each link below to access CTRC Core services.


CHOP Specific Procedures for CTRC Research Nursing Core (RNC)

The Clinical and Translational Research Center (CTRC) is staffed by experienced, qualified research nurses for inpatient and outpatient activities. The nurses, medical assistants and lab techs support a wide variety of research protocols. CHOP CTRC Nursing support is available at two outpatient locations at Main and 3550 Market Street, the CTRC Inpatient Unit on 5 West, and other CHOP inpatient units as necessary.

The Nutrition Core has two components. The Nutrition Assessment Unit is a state-of-the-art facility for the assessment of growth and body dimensions, body composition (the amount of muscle, fat and bone in the body), energy expenditure, bone density, and muscle strength. The Core provides consultation and technical expertise for these assessments. The Unit has two locations and four experienced research technicians for performing nutrition assessments. The Dietary Assessment Unit is staffed by experienced registered dietitians and provides a broad range of nutrition-related research services to investigators.
The CTRC Sleep Core provides services in support of clinical sleep research. It is based at two sites: the CHOP Sleep Laboratory, convenient to the CTRC Outpatient Facility on the First Floor of Main Hospital and the University of Pennsylvania's Sleep Laboratory, located on the 11th Floor of the Gates Building which is part of the medical complex of the Hospital of the University of Pennsylvania. The Sleep Core contains a total of six designated research beds, dedicated staff, and state-of-the-art equipment that provides support for a variety of sleep-related research initiatives.

The CTRC Cardiovascular Core provides cardiac testing services at CHOP for pediatric subjects in the Main Building. Services for adult subjects MUST be discussed with the CTRC Cardiovascular Core Director, Dr. Meryl Cohen, MD.

The Behavioral Neuroscience Core provides consultation and assistance to investigators regarding psychological, neuropsychological, and psychiatric components of research studies involving pediatric subjects. The Core is highly experienced in implementing multisite protocols. We provide test kits, test record forms, and scoring software at no additional charge to the investigators for whom we provide testing services. When investigators are considering work with the Neurobehavioral Core, it is helpful to provide a copy of the protocol prior to submission, so that our Core can determine our ability to conduct testing and procedures that are called for, as well as to give estimates as to the costs for each study evaluation.
Study Design and Biostatistics provides research study planning and analytic services, such as study design, sample size estimation, analysis planning, as well as production of statistical reports and graphical displays.

The Informatics Core provides assistance with database development and CRF form development and other computing needs.

The Clinical and Translational Research Center (CTRC) offers ophthalmological testing services for children. The Ophthalmology Core at CHOP's CTRC was established to provide clinical and translational research services in ophthalmology for the assessment of visual function and structure.

The Pediatrics Research Consortium (PeRC) supports effective research within the Children’s Hospital community by coordinating our extensive practice-based research network (PBRN). We cater to the diverse needs of the three main parties that benefit from practice-based research: 1) Researchers, 2) Care Centers and Practices, and 3) Patients and Families.